Nov 1, 2010
Posted in Fertility, News

Being Blood Group O and Effects on Fertility

Increasing numbers of females are presently opting for in-vitro fertilization treatment – with figures skyrocketing to over ten times from the early 1990 mostly due to the rising trend of deferring maternity till later on in life.

However at present it appears that a female’s prospects of getting pregnant in her thirties and forties might not be depending solely on how old she is but also what is her blood group which additionally impacts her fertility, as per scientists from the Albert Einstein College of Medicine, N.Y.

The study finding suggests that particularly females from blood group O – the most pervasive group – had lesser egg numbers and shoddier quality of eggs in their thirties as compared to females belonging to blood group A.

Basically, everybody comes under 4 major blood types, namely, AB, O, A, B & a number of sub-types for every one of these ( for example, those with O blood group could be RhD +ve or RhD –ve ) & the type one has is dependent on one’s heritable constitution.

In case the mother and father belong to blood group O then the child too would have the analogous blood type. Beyond this there are no outlined rules. For instance despite parental blood group being A yet the offspring can yet have a blood group O.

The variation in-between the blood groups is ascertained by the type of proteins present on the exterior of the RBCs – in case one has O form of proteins then one is categorized as type O.

The Plausible Link between Blood Type and Fertility

A female’s blood type seems to be an influencing factor in the levels of FSH or follicle stimulating hormone that her body manufactures. Research has shown that elevated amounts of FSH are an indication of infertility, particularly being that of squat ovarian reserve (egg count remaining at any given instant). It is a number varying in every female and could plummet due to endometriosis (an agonizing condition when the cells that line the uterus breakdown), ovarian cyst presence and among smokers.

Females have an innate supply of eggs at birth (around 2 million) & do not manufacture any further. This figure dips all through life however the plummet accelerates post thirty-seven years of age & the time a female becomes menopausal, solely about ten thousand eggs remain. Though the number may be sounding ample however egg quality is pitiable at that time.

FSH measurement is done in units/litre blood and readings of over 10 are indicative of a female facing problem trying to get pregnant. A novel trial found that females in their mid-thirties who struggle to get pregnant had a two-fold greater likelihood of having augmented FSH levels in case they belonged to blood group O rather than of group A.

Additionally, several specialists deem that blood group has an impact on the immune system’s response to tried conceptions. It is identified amongst IVF experts that immune systems of females don a key part in ascertaining successes of egg embedding. Females of blood group O have the smallest likelihood of meeting success in in-vitro fertilization treatment since they mostly are experiencing inapt immune responses. At the time of conceiving, the maternal shields need to increase what is known as an apt immune response. It is where the immune system comprehends tolerating the alien matter from the male sans attacking it.  It is considered that blood group O tends to disrupt such a delicately-tuned response.

Ways of Testing Egg Left in a Woman

Ultrasounds are far sharper means of checking the antral follicle numbers (these are follicles in a state of dormancy though containing high egg reserves). It checks the numbers of such follicles remnant in the ovaries of a woman.

Another method is blood testing or checking amounts of anti Mullerian hormone which is manufactured by unripe eggs within the ovaries and is deemed by several experts as an abler indication of ovarian reserves.

What could be done for boosting fertility?

Inevitably one can’t alter one’s blood group however till additional studies are conducted for proving if it truly could decide a woman’s prospects of conception one could halt the habit of smoking, maintain ideal weight and avoid excess alcohol consumption which are believed to hamper fertility.

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