Aug 3, 2010
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Actress Christina Applegate’s Pregnancy following Breast Cancer Therapy is Safe



After having successfully trounced breast cancer, the ex-sitcom celebrity, thirty-eight year old Christina Applegate is moving on to possibly her trickiest role ever – maternity.

Lately Applegate announced her pregnancy which has come 2 years following a double mastectomy surgery she underwent in July. She mentioned on ‘Good Morning America’ that around a month’s time post-surgery she was totally free of cancer.

For Breast Cancer Survivors – Pregnancy No Hurdle

Specialists state that although females do tend to be anxious about conceiving after breast cancer treatment, research findings have indicated that getting pregnant after some span of time or time-gap following breast cancer therapy carries no greater risk than conceiving any other time.

Doctors however point out that conceiving soon following therapy might be linked to an augmented risk of the breast cancer recurring.

Without a doubt, studies have proven that conceiving might in fact shield the female from a cancer relapse.

Researches have shown better results among females that ultimately conceived following 2-5 years. Physicians point out that pregnancy is perhaps a shielding effect as there are lesser ovulation cycles hence lesser estrogen presence.

Apt Time-Frame Might Differ

Advice on what is deemed a risk-free time for females to conceive varies from case to case and is mostly based on how old the woman is and the cancer staging, however physicians usually stick to a benchmark procedure.

Gynaecologists recommend that among females who have undergone chemotherapy and surgical procedures and tended to their cancer should ideally wait for 2 years till that are completely free of cancer.

Other recommendations to women intent on bearing children after surviving breast cancer, based on their condition are as follows:

  • Women in the older age bracket not intent on waiting for 2 years could opt for cryopreservation (freezing embryos) or go in for donor egg afterwards.
  • Females with later staging of breast cancer, based on the amount of remnant tumor and whether they require chemo, must not conceive.
  • Females with estrogen positive type of cancer and taking medication course comprising of tamoxifen should ideally complete the drug course and then conceive since it has been linked to birth anomalies.
  • Females who are carriers of a heritable mutation which tends to predispose them to getting cancer are also at an elevated risk of developed other cancer forms and must undergo meticulous screening prior to attempting conception.
  • In case of other chemo medications, in case therapy is ceased for an apt period then physicians state that there is no problem is such cases to go ahead with pregnancy. Since females have stopped chemotherapy then there is no risk of any associated side-effects.

The kids of women who underwent breast cancer treatment are additionally at no higher risk of getting cancer later on in their life.

Many large-scaled trials have substantiated that kids of mothers who earlier had cancer are in as good health as the rest of the non-cancerous populace.

Fertility Concerns

Even as Christina Applegate is a shinning exemplar that conceiving post-breast cancer therapy is possible, yet physicians state that there might be fertility problems based on how old the woman is and the chemotherapy type she has been through.

Several chemotherapy drugs could have a damaging effect on the ovaries and be causal to early menopause. Although a number of females below forty do get their menses post-chemotherapy, hence there aren’t inevitably infertility problems.

Even as Christina Applegate is free from cancer and despite undergoing double mastectomy procedure for total breast tissue removal, several females in such cases are not essentially risk-free. In case there are remnant estrogen receptors still present in the body there might be a higher risk of relapse. When there is no breast left then risk are quite less, however cancer could yet spread to a lymph node.

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