Feb 10, 2011
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In Vitro Fertilization – How Safe is it for Women?



Females who are thinking about trying in vitro fertilization for infertility issues must be better informed regarding the associated risks. It is particularly pertinent for older females or those with some health issues, according to a report conclusion appearing in the British Medical Journal which examines safety of gestation & delivery following in-vitro fertilization.

In vitro fertilization (IVF) – What’s already known?

Though IVF method is safe for majority of the females, however it isn’t risk-free. Several forms of IVF entail the use of elevated hormonal dosages for ovarian stimulation that could be causal to an atypical, perilous situation known as ovarian hyperstimulation syndrome.

Moreover, IVF might in an indirect manner augment risks of gestation & birthing by amplifying the likelihood of twin or more pregnancies (in case over a single embryo implantation is done) or by augmenting the number of older-age females conceiving. Females in their mid-thirties onwards & those with more than one pregnancy would be facing more risk of complication all through gestation & child delivery.

Researches have proven that figures related to gestational or delivery deaths subsequent to in vitro fertilization, though less; surpass those of females conceiving without opting for IVF. Mortalities during gestational period or delivery – that had become quite atypical, are gradually rising in the United Kingdom – perhaps reflecting the augmented number of older females conceiving & the augmented usage of IVF.

What the current research indicates?

Authors were looking into the latest study that probes the safety & risks of opting for in vitro fertilization among females. They stated that, though mortalities rarely occur, they are yet occurring in the United Kingdom. Reports of 4 mortalities due to ovarian hyperstimulation syndrome occurred during 2003-2005, these are the recent time period of which numbers are obtainable.

The scientists added that physicians must ensure that they are reporting ovarian hyperstimulation syndrome to ably understand its pervasiveness. They additionally stated that females, especially the ones having fundamental health issues, must be receiving additional info regarding risks of gestation prior to them starting off with IVF.

When the sum numbers of female mortalities during gestation & delivery were examined, the authors draw attention to a latest Netherlands-based trial. It computed that, in comparison to a nationwide maternal mortality rate of thirteen for each one lakh expectant mothers, the occurrence for maternal mortality post-IVF was forty-three for each one lakh expectant mothers.

What is the reliability of the study findings?

The authors state that they require improved understanding regarding gestational & delivery risks post-IVF. They advice that there must be central gathering of info regarding complication or mortality during IVF gestation & delivery which would help physicians & females to be better aware and informed about the risks.

Where does the trial originate?

Trio gynaecologists who work in hospitals at London have penned down the report which appeared in the BMA’s British Medical Journal.

What the trial means for women?

In case a woman is mulling over trying IVF, there are several aspects to be taken into consideration like probability of successes, if one would be paying for the therapy & what the effects might be on the future. The report starkly reminds one and all that IVF isn’t without risks.

What must women be doing presently?

In case a woman plans to opt for IVF then she must be discussing with her doctor regarding risks of gestation & child delivery. She must also inquire about ways of minimizing such risks; for instance, by getting single embryo implantation instead of duo or multiple. Women deciding on IVF also need to be in good overall health prior to commencing the treatment which is a pre-requisite for physicians.

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